Completed projects
- Development of molecular MR temperature probes
- Fluorinated boron clusters in cell culture
- Parahydrogen-induced nuclear spin hyperpolarization of fluorinated substrates - standard PHIP
- Parahydrogen-induced nuclear spin hyperpolarization - studies using the SABRE method
- Enhancement of MR sensitivity of 19F biomarkers and PET-analogous 19F-labeled receptor ligands by para-hydrogen-induced polarization
Research focus
19F NMR spectroscopy and MR imaging
- Enhancement of MR signals by parahydrogen-induced hyperpolarization (PHIP: PASADENA, ALTADENA, SABRE) and photo-CIDNP
- Cell labeling with MR-sensitive fluorinated substances for non-invasive observation of cell migration in tumor treatment
- Temperature determination using fluorinated markers and MR spectroscopy
- Synthesis and characterization of new water-soluble fluorinated compounds
Viability measurements in cell culture
- Review of the toxicity and stability of organic compounds regarding their toxicity and stability on fibroblasts and melanoma cells